Our research interests stretch across the field of organic chemistry from traditional areas, such as synthetic methodology development and natural product synthesis to bioorganic chemistry, including enzyme inhibitor design, synthesis and testing. Despite a broad range of research interests, our primary laboratory activities involve organic synthesis. There are currently two active projects: indoleamine 2,3-dioxygenase (IDO) inhibitor design and synthesis and natural product synthesis with the sequential Birch reduction-allylation and Cope rearrangement. The ultimate goal of both projects is to develop new therapeutics for the treatment of a variety of ailments, most notably cancer and neurodegenerative diseases.
Group Members (INCLUDING GROUP PHOTOS!!)
Fall 2008 Courses:
Research Methodology (CHEM 251)
Organometallic Chemistry (CHEM 534)
Past Courses:
Advanced Organic Chemistry: Synthesis (CHEM 311/511)
Organic Chemistry 2 (CHEM 212)
Topics in Organic Chemistry: Modern Medicinal Chemistry (CHEM 515)
General Chemistry 1 (CHEM 103)
William P. Malachowski
Associate Professor of Chemistry
Education:
B. A., College of the Holy Cross, 1987
Ph. D. The University of Michigan, 1993 (Advisor:Prof. J. K. Coward)
Previous Positions:
Postdoctoral Associate Rensselaer Polytechnic Institute, 1993-6
(Advisor: Prof. A. G. Schultz)
Assistant Professor of Chemistry, University of New England, 1996-2000
Mail Address:
Department of Chemistry
101 N. Merion Ave.
Bryn Mawr, PA 19010
Office: 270 Park Science Center
Phone: 610-526-5016
Fax: 610-526-5086
Lab Phone: 610-526-7454
e-mail: wmalacho@brynmawr.edu