Bill Malachowski
Research
Our research interests stretch across the field of organic chemistry from traditional areas, such as synthetic reaction development and natural product synthesis to bioorganic chemistry, including enzyme inhibitor design, synthesis and testing. In all these fields, our primary laboratory activities involve organic synthesis or constructing molecules. There are currently two active projects in the group:
- Indoleamine 2,3-dioxygenase inhibitor design and synthesis (IDO project)
- Natural product synthesis with the sequential Birch reduction-allylation and Cope rearrangement (Birch-Cope project)
The ultimate goal of both projects is to develop new therapeutics for the treatment of a variety of ailments, most notably cancer and infectious diseases.
Group Members (INCLUDING GROUP PHOTOS)
Teaching and Course Information
Spring 2013 Course:
Biological Organic Chemistry (CHEM 212)
Past Courses:
Organic Chemistry 1 (CHEM 211)
Organic Chemistry 2 (CHEM 212)
Organometallic Chemistry (CHEM 334/534)
Medicinal Chemistry (CHEM 315/515)
Research Methodology (CHEM 251)
Drugs & How They Work (CHEM 116)
Advanced Organic Chemistry: Synthesis (CHEM 311/511)
General Chemistry 1 (CHEM 103)
Links
William P. Malachowski
Professor and Chair of Chemistry
Education:
B. A., College of the Holy Cross, 1987
Ph. D. The University of Michigan, 1993 (Advisor: Prof. J. K. Coward)
Previous Positions:
Postdoctoral Associate,
Rensselaer Polytechnic Institute, 1993-6
(Advisor: Prof. A. G. Schultz)
Assistant Professor of Chemistry, University of New England, 1996-2000
Mail Address:
Department of Chemistry
101 N. Merion Ave.
Bryn Mawr, PA 19010
Office: 270 Park Science Center
Phone: 610-526-5016
Fax: 610-526-5086
Lab Phone: 610-526-7454
e-mail: wmalacho@brynmawr.edu