Organometallic
Chemistry
when - Tues/Thurs 10:00 - 11:30
where - Park 264
why - to introduce the basics of a vital interdisciplinary area of chemistry
what - what happens when an organic chemist discovers the transition series
or
what happens when an inorganic chemist gets bored with available ligands
how - 1. two exams
-one mid-term during the week of Oct. 18
-one final during Finals period
2. one
paper discussion
- lead the discussion of a recent
selected paper on organometalllic chemistry
3. the Tuesday Terror!
-each Tuesday two students chosen at random from all class members will lead the discussion and solution to a problem that relates to ideas recently covered in class.
The ‘problem’ to be discussed can arrive to you in several ways:
- it may be a problem that is handed out to the entire class during the preceding
Thursday session.
- it may be a “pop” question with no prior hints
- it may be based on a short article from the literature
Grade
2 exams 50% (25% each)
1 presentation 25%
Tuesday Terror 25%
Date chapter lecturer topics
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Aug. 31 |
1 |
B |
Coordination chemistry refresher |
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2 |
B |
The Power and Confusion of the 18 electron Rule |
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3 |
M |
Metal Alkyls |
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4 |
B |
L-type ligands and what they do and how to know it |
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5 |
B, M |
Mono-enes, poly-enes and ring-enes |
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6 |
B |
OA / RE = 1 |
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7 |
M |
Squeezed in and squeezed out: insertions and eliminations |
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8 |
M |
Nucleophilic & Electrophilic Reactions |
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9 |
M |
Homogeneous Catalysis |
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10 |
M |
What’s going on in the flask? How can we tell? |
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11 |
B, M |
Carbenes, carbines, carbones… |
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12 |
B |
Making the Unreactive React |
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13 |
B |
Clusters and how to make sense of them |
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14 |
M |
Applications to Organic Syntheses |
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Organometallic topics:
pi-bonding
18 e- rule
ligand types (X -, alkyl, carbene/alkylidene, carbyne/alkylidyne, pi-acids, pi-bases,
metal hydrides, metal-metal bonds, conjugated polyenes )
electron counting
electronic effects
characteristics of carbene/alkylidene, carbyne/alkylidyne ligands
NMR characterization of M-C bonds; fluxionality, importance of coupling constants
Types of Reactions: ligand substitution
oxidative addition
reductive elimination
insertions/migrations
cyclometallations
Catalytic Processes Important in Industry and Organic Synthesis:
hydrogenations
hydrozirconation
hydroformylation
asymmetric reactions
olefin metathesis and polymerization