CHEM 534 - Fall 2004

                                   

Organometallic Chemistry

 

when  - Tues/Thurs 10:00 - 11:30

 

where  - Park 264

 

why  -  to introduce the basics of a vital interdisciplinary area of chemistry

 

what  -  what happens when an organic chemist discovers the transition series

                        or

              what happens when an inorganic chemist gets bored with available ligands

 

how  - 1. two exams

            -one mid-term during the week of Oct. 18

            -one final during Finals period

 

 2. one paper discussion

           

            - lead the discussion of a recent selected paper on organometalllic chemistry

 

 3. the Tuesday Terror!

 

            -each Tuesday two students chosen at random from all class members will lead the        discussion and solution to a problem that relates to ideas recently covered in class.

 

            The ‘problem’ to be discussed can arrive to you in several ways:

                       

-         it may be a problem that is handed out to the entire class during the preceding

      Thursday session.

                        - it may be a “pop” question with no prior hints

                        - it may be based on a short article from the literature

 

 

Grade

 

            2 exams                        50% (25% each)

            1 presentation               25%

            Tuesday Terror 25%

 


 

    Date                        chapter            lecturer                                                topics

Aug. 31

1

B

Coordination chemistry refresher

 

 

 

 

 

2

B

The Power and Confusion of the 18 electron Rule

 

 

 

 

 

3

M

Metal Alkyls

 

 

 

 

 

4

B

L-type ligands and what they do and how to know it

 

 

 

 

 

5

 B, M

Mono-enes, poly-enes and ring-enes

 

 

 

 

 

6

B

OA / RE = 1

 

 

 

 

 

7

M

Squeezed in and squeezed out: insertions and eliminations

 

 

 

 

 

8

M

Nucleophilic & Electrophilic Reactions

 

 

 

 

 

9

M

Homogeneous Catalysis

 

 

 

 

 

10

M

What’s going on in the flask? How can we tell?

 

 

 

 

 

11

B, M

Carbenes, carbines, carbones

 

 

 

 

 

12

B

Making the Unreactive React

 

 

 

 

 

13

B

Clusters and how to make sense of them

 

 

 

 

 

14

M

Applications to Organic Syntheses

 

 

 

 




 

 

 

 

Organometallic topics:

 

            pi-bonding

            18 e- rule

            ligand types (X -, alkyl, carbene/alkylidene, carbyne/alkylidyne, pi-acids, pi-bases,

                                    metal hydrides, metal-metal bonds, conjugated polyenes )

            electron counting

            electronic effects

            characteristics of carbene/alkylidene, carbyne/alkylidyne ligands

            NMR characterization of M-C bonds; fluxionality, importance of coupling constants

            Types of Reactions:      ligand substitution

                                                oxidative addition

                                                reductive elimination

                                                insertions/migrations

                                                cyclometallations

            Catalytic Processes Important in Industry and Organic Synthesis:

                                                hydrogenations

                                                hydrozirconation

                                                hydroformylation

asymmetric reactions

                                                olefin metathesis and polymerization