Organometallic Chemistry (CHEM 534)

Fall 2008
Prof. W. P. Malachowski
Office: Park 270
Phone: Ext. 5016
e-mail: wmalacho@brynmawr.edu
web page: http://www.brynmawr.edu/chemistry/malachowski
course web page: http://www.brynmawr.edu/chemistry/malachowski/Organometallics/Organometalintro.html

Class Meetings:
Tues., Thurs. 11:40-1:00 PM
All class meetings will be held in Park 278.  Class cancellations, i.e. for inclement weather, will be posted on the course website and/or communicated via e-mail.

Office Hours:  Mon. 4:00-5:00 PM, Wed. 9:30-11:00 AM and by appointment.

Lecture Textbook: The Organometallic Chemistry of the Transition Metals, 4th Edition, by Robert H. Crabtree

Additional References:

Advanced Organic Chemistry, Part B: Reactions and Synthesis, 4th edition (2001) by Francis A. Carey and Richard J. Sundberg

Comprehensive Organometallic Chemistry, (1982) eds. G. Wilkinson, F. G. A. Stone, E. W. Abel
Comprehensive Organometallic Chemistry II, (1995) eds. G. Wilkinson, F. G. A. Stone, E. W. Abel

Encyclopedia of Reagents for Organic Synthesis, (1995) Leo Paquette
Handbook of Reagents for Organic Synthesis (1999)
Organometallic chemistry, (1997) Gary O. Spessard, Gary L. Miessler

Principles and Applications of Organotransition Metal Chemistry, (1980) James P. Collman, Louis S. Hegedus

 

Online Resources:

Organometallic HyperTextBook: http://www.ilpi.com/organomet/

                                                                                                             

Class Schedule:  

Week

Tuesday

Thursday

Lecture Topic (Text Reading)

1

9/2

9/4

Transition metal complex basics (Ch. 1 and 2)

2

9/ 9

9/11 PS#1

Metal alkyls (Ch. 3)

3

9/16

9/18

L-type ligands (Ch. 4)

4

9/23 PS#2

9/25

Pi-bound complexes (Ch. 5)

5

9/30

10/2 PS#3

Oxidative addition and reductive elimination (Ch. 6)

6

10/7

10/9 Exam 1

Insertions and eliminations (Ch. 7)

Fall Break

10/11-10/19

 

 

7

10/21

10/23 PS#4

Nucleophilic and electrophilic reactions (Ch. 8)

8

10/28

10/30

Homogeneous catalysis (Ch. 9)

9

11/4 PS#5

11/6

Analysis of organometallic reactions (Ch. 10)

10

11/11

11/13 PS#6

M-L multiple bonds (Ch. 11)

11

11/18

11/20

Applications in organic synthesis (Ch. 12 and 14)

12

11/25 Exam 2

Thanksgiving Break

Open

13

12/2

12/4

Student Oral Presentations

14

12/9

12/11

Student Oral Presentations

 

Problem Sets: There will be six take-home problem sets which will be collected at the beginning of class on the date shown on the schedule above.  You may work in study groups to complete the problem sets, but you should submit your own version of the problem set solution.

 

Exams: There will be two mid-semester exams given during the class meeting time on October 9 and November 25.

 

Oral Presentation: Students will work in groups of two or three to present a recent article from the organometallic chemistry literature to the class. The literature article will be chosen by the students from a selection of articles on organometallic chemistry topics assembled by the instructor. Student groups will have 30-45 minutes to deliver a presentation which explains the context and significance of the literature article while exploring the experimental details of the research.

 

Final Exam: There will be a three-hour self-scheduled final exam without lecture notes, textbook or any other associated course materials.
 

Course Grading:

Problem Sets

20 pts. (x6)

=120 pts.

Mid-term Exams

100 pts. (x 2)

=200 pts.

Oral Presentation

 

=100 pts.

Self-scheduled Final Exam

 

=150 pts

 

 

________

570 pts.

 

Approximate Grading Scheme:

93-100%  4.0 (A)

70-73%   2.0 (C)

89-92%    3.7 (A-)

66-69%   1.7 (C-)

85-88%    3.3 (B+)

62-67%   1.3 (D+)

81-84%    3.0 (B)

58-61%  1.0 (D)

77-80%    2.7 (B-)

<57%  0.0 (F)

73-76%    2.3 (C+)

 

 

 

I reserve the right to make modifications to this scheme when I consider it necessary.

 

Students with Disabilities:  Students who think they may need accommodations in this course because of the impact of a disability are encouraged to meet with me privately early in the semester.  Students should also contact Stephanie Bell, Coordinator of Access Services, at 610-526-7351 or sbell@brynmawr.edu, as soon as possible to verify their eligibility for reasonable accommodations.  Early contact will help to avoid unnecessary inconvenience and delays.