Bryn Mawr College

Department of Chemistry

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wpm in lab

William P. Malachowski
Associate Professor of Chemistry

Education: 
    B. A., College of the Holy Cross, 1987 
    Ph. D. The University of Michigan, 1993 (Advisor:Prof. J. K. Coward) 

Previous Positions: 
    Postdoctoral Associate Rensselaer Polytechnic Institute, 1993-6
        (Advisor: Prof. A. G. Schultz) 
    Assistant Professor of Chemistry, University of New England, 1996-2000 

Mail Address:
    Department of Chemistry
    101 N. Merion Ave.
    Bryn Mawr, PA 19010

Office: 270 Park Science Center 
Phone: 610-526-5016 
Fax: 610-526-5086 
Lab Phone: 610-526-7454
e-mail: wmalacho@brynmawr.edu

Research

Our research interests stretch across the field of organic chemistry from traditional areas, such as synthetic methodology development and natural product synthesis to bioorganic chemistry, including enzyme inhibitor design, synthesis and testing. Despite a broad range of research interests, our primary laboratory activities involve organic synthesis.  There are currently two active projects: indoleamine 2,3-dioxygenase (IDO) inhibitor design and synthesis and natural product synthesis with the sequential Birch reduction-allylation and Cope rearrangement.  The ultimate goal of both projects is to develop new therapeutics for the treatment of a variety of ailments, most notably cancer and neurodegenerative diseases.  

Publications

Grant Support

Group Members (INCLUDING GROUP PHOTOS!!)

Teaching and Course Information

Spring 2008 Courses:

Organic Chemistry 2 (CHEM 212)

Past Courses:

Research Methodology (CHEM 251)

Advanced Organic Chemistry: Synthesis (CHEM 311/511)

Topics in Organic Chemistry: Modern Medicinal Chemistry (CHEM 515)

Organometallic Chemistry (CHEM 534)

General Chemistry 1 (CHEM 103)

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