INSTITUTIONAL ANIMAL CARE AND USE PROTOCOL

Title of Project:

II. Principal Investigator:

III. Department:

IV. This protocol is ____ new, __ revised:

(If revised, give date of original approval_____

V. This protocol is needed for which of the following:

grant _____ contract _____ fellowship ______ teaching

______ other (specify)

If grant, contract, or fellowship, specify the funding agency

VI. If a letter of approval is needed for the funding agency, give the name and address of the person to whom it should be sent.

VII. Describe the overall purpose of this project and point out its significance.

VIII. What is the rationale for using animals in the project? The rationale for this particular species, and for the number of animals to be used?

IX. (a) Describe in some detail the procedures to be employed in this work.

(b) Give particular attention to any surgical procedures and describe the immediate and long-range post-operative care procedures, including provisions for care after working hours (including weekends and holidays).

(c) Describe in detail any procedure involving pain to the animals, and discuss any pain-relieving techniques to be employed or justify their non-use.

X. Provide full information about all drugs to be used and the reasons for their use. Describe any side effects to be expected.

XI. Describe the method of euthanasia to be employed. (Note that ether cannot be used as a euthanizing agent because of its explosive properties. Cervical dislocations or decapitations are not acceptable for animals weighing over 250 grams without anesthesia, unless justified for scientific reasons.)

XII. Describe the training of instruction concerning care and treatment of animals that will be given to personnel in the project.