Steffany Chou
Dr. Jason Schmink
Chemistry

Palladium Catalyzed Cross-Coupling of 1,3-Oxathiolanes and Aryl Bromides

Our lab explores palladium catalysis and the development of alternative nucleophiles. The focus of our research this summer will be to optimize the synthesis of aryl vinyl sulfides from the palladium catalyzed cross-coupling reaction of 1,3-oxathiolanes and aryl bromides. Such sulfide compounds are significant in organic chemistry syntheses, and have applications in both pharmaceuticals and materials sciences. We will be analyzing the data of reactions run under varying conditions to find the most efficient methods of synthesis, while striving to remain within the principles of green chemistry.