Attachment of ruthenium (II) polypyridyl complexes to single walled carbon nanotubes

Mentor: Dr. Sylvia Porello

 

Carbon nanotubes (CNTs) have received much attention for potential biomedical applications including drug delivery and targeted treatment. Recently there have been many efforts to functionalize CNTs with metal complexes because such binding would open up arrays of opportunities for CNT application in nanotechnology. Ruthenium complexes have been studied extensively for their ability to intercalate into DNA. The ligands on these complexes determine how they interact with DNA. Previous studies have shown successful attachment of ruthenium (II) complexes to single walled carbon nanotubes (SWCNTs). The goal for research this summer include [1] attaching Ru (II) compounds to SWCNTs and [2] characterizing the composites and examining their interactions with DNA. The project will focus on noncovalent attachment of [Ru(bpy)2(L-allox)]2+ and [Ru(bpy)2(L-Me2Allox)]2+ to SWCNTs. The attachment will be confirmed by the changes in fluorescence and absorbance properties. Then the interaction between these Ru (II) complex--SWCNT composites and DNA will be studied.