Asymmetric construction of sulfur(VI)-fluorine cores
Author: Patrick Melvin
Source: Nat. Chem. 16, 304–305 (2024). https://doi.org/10.1038/s41557-024-01454-8
Publication Type: News Item
Abstract: Molecules containing a chiral S(VI) moiety have found extensive applications in drug design and organic synthesis, despite a lack of diverse asymmetric methods for their creation. Now, a ligand-mediated process has enabled the production of enantioenriched S(VI)-F motifs, providing a foundation for further stereospecific elaborations.
Chemistry
